Expert services in mass spectrometry™

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Mass spectrometry services

Meet our staff

Hugo Gagnon, Ph.D.

Chief executing officer

Hugo Gagnon is co-founder of PhenoSwitch Bioscience. Coming from a small town named Riviere-du-Loup, which apparently has one of the most beautiful sunsets, he moved to Sherbrooke to play football and start his biochemistry B.Sc. and Pharmacologist (M. Sc.). He taunted the mass spectrometer during its co-guardianship in Biochemistry (Ph.D. Université de Sherbrooke) and life science (Ph.D. Université Lille 1). Amazed by how mass spectrometry could drive projects, highly inspired by former French colleagues involved in the startup of Imabiotech and looking to do things differently, he jumped with its former Ph.D. mentor into entrepreneurship. He is behind the knowledge and the know-how of innovative LC-MS/MS services offered at PSB. Team work, thinking outside the box, project seed driver and a strong willing to make things move forward characterize him. Enjoys sports and manual labor, he is fortunate enough to have a lovely family to bring him back to earth when his is again thinking about Science.

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Phone (ext 11)

Karine L'Ériger, M.Sc.

Administrative assistant/Marketing manager

Karine L’Ériger is an Administrative Assistant/Marketing Manager at PSB. She loves multidisciplinary works and team work. Her word of choice is «efficiency», optimization of processes to achieve good results is her  strength. After obtaining a B.Sc. in Biochemistry and a M.Sc. in Cell Biology from University of Sherbrooke, Karine was determined to learn the administrative aspect of an organization. She wanted to be in the service of science rather than to make science. Then, she earned a certificate in Business Administration and an Accounting certificate from University of Sherbrooke. Her work is to provide administrative support, create work tools adapted to the needs of PSB and to communicate the benefits of doing business with PSB. She enjoys relaxing by doing outdoor activities with her family and by experimenting urban agriculture. She is in constant search of a perfect balance between work and family.

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Jean-Philippe Couture, Ph.D.

Application specialist/Director of Marketing

Jean-Philippe came to Sherbrooke in 2005, after completing a B.Sc. in biology at the Université du Québec à Chicoutimi. He started his graduate studies working on the role of a protein kinase in adipogenesis, where he managed to master a lot of the techniques required to study cell signaling. After getting his Ph.D., Jean-Philippe completed a first post-doc in the regulation of transcription, before knocking at the door of PSB, asking for a job. Since then, he specializes in the development of IP-MS strategies and works towards increasing the company’s client pool. After two years in the company, Jean-Philippe was given the opportunity to lead the marketing strategy of the company. Apart from science, Jean-Philippe enjoys playing sports, making music with friends and spending quality time with his family.

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Jean-François Noël, Ph.D.

Application specialist/Lab Director

Jean-François completed a B.Sc. in biology and a Ph.D in microbiology, both from the Université de Sherbrooke. Interested in genome integrity, cancer and aging, Jean-Francois spent the better part of his graduate studies conducting research in the field of telomere maintenance and telomerase biogenesis, working with yeast as a model organism. But during his scientific journey, he also contributed to a variety of projects, notably in DNA damage & repair, RNA splicing and maturation, mobile genetic elements, chromosome dynamics and cellular senescence. At PSB’s, Jean-Francois is now working on the development of strategies for abundant protein depletion from plasma samples. He is also dedicated to SWATH, a data-independent MS acquisition method allowing widespread quantification of all detectable proteins present in a sample. So going from brewer’s yeast genetics to human plasma proteomics is not a step as big as it seems!

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Nicolas Dory

Lab technician

Nicolas studied Analytical Techniques in Biotechnologies at Cegep de Sherbrooke. He likes teamwork and is always eager to increase his knowledge base. Perfectionism describes him well. As such, he is passionate about lab work. At PSB, Nicolas executes a large selection of sample preparation protocols. His main goal is to provide exact and meaningful results to our clients.

 

 

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Kévin Ly, Ph.D.

Application Specialist

Kévin Ly started his undergraduate study in Pharmacology (B.Sc.) at Université de Sherbrooke (UdeS) in 2006. He obtained a Ph.D. in Biochemistry in 2016 under the supervision of Pr. Robert Day at the Institut de pharmacologie de Sherbrooke. His doctoral research project focused on the regulation of PCSK9, a key player in LDLR degradation and LDL-cholesterol homeostasis. He developed and conducted various cell-based assays and in vivo studies to evaluate the potential of peptide-based PCSK9 inhibitors as cholesterol-lowering drugs. During his studies, Kévin acquired knowledge on protein purification, protein-protein interactions, molecular modeling, peptide and peptidomimetic inhibitors, and in mass spectrometry. Now, Kevin is eager to share his skills and know-how as a member of PhenoSwitch to help clients reach their needs and goals. On a personal note, Kévin enjoys outdoor activities, photography, cinema and thrilling activities.

 

 

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PhenoSwitch Bioscience team.

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ESI source TripleTOF 5600

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Experts in mass spectrometry

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The entrance of the mass spec

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Mass spectrometry sample preparation

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M3 High performance micro LC

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Front end QTRAP 6500+

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Closeup shot of the microchips and fluidics of the Eksigent micro LC

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IonDrive QJet guide

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Curtain plate TripleTOF 5600

The whole team!

Have a look to our labs and our machines!

Click on the images for a small description

  • The PhenoSwitch team, hard at work!

    The PhenoSwitch team, hard at work!

    The scientists at PhenoSwitch Bioscience work for you, and with you. Our team will perform high quality sample preparation and mass spectrometry analysis to get your drug developed and/or your paper published faster.

  • ESI source of our TripleTOF 5600

    Close up shot of our TripleTOF 5600

    This is where the magic begins! This part of the mass spectrometer is referred to as the source. This particular source ionises the molecules by applying a high voltage to the tip of the probe in a process that is known as "Electrospray Ionisation" (ESI). The ions are then sucked into the MS and recorded.

  • We're experts in mass spectrometry

    Our Ph.D. level scientists work for you

    Our team gather more than 20 years of combined academic research expertise. We will put everything we know at your service.

  • Artistic shot of our ESI source of our TripleTOF 5600

    Artistic shot of our ESI source of our TripleTOF 5600

    Complicated technological pieces don't have to be hideous. This is the perfect example!

  • The entrance of the mass spec

    The entrance

    This is a photograph of the second quadrupole of our QTRAP 6500+. It is referred to as the Q0. It lies after the QJet and before Q1.

  • Mass spectrometry sample preparation

    Mass spectrometry sample preparation

    The cornerstone of a good mass spec experiment is the sample preparation. Our team will guide you through MS-compatible protocols or perform the experiments for you.

  • Mass spectrometry sample preparation2

    High tech science.. but still science!

    We're equipped with the latest technology in mass spectrometry. But we also have basic science tools!

  • High performance micro LC

    High performance micro LC

    Sample preparation is important, as is a good mass spectrometer. However, proper molecule separation before the MS analysis is also of paramount importance. This is why our machines are equipped wih high performance micro HPLC from Eksigent.

  • Front end of the QTRAP 6500+

    Stylish front end of our QTRAP 6500+

    This is a front view of our QTRAP 6500+. As our TripleTOF 5600, the QTRAP is equiped with an ESI source.

  • Closeup shot of the microchips and fluidics of the Eksigent micro LC

    Closeup shot of the microchips and fluidics of the Eksigent micro LC

    Microchips, tiny pipes and microfluidics. Looks neat, right?

  • IonDrive QJet guide

    IonDrive QJet guide

    The IonDrive QJet guide is located right after the curtain plate, but before the Q0 quadrupole. It's role is to focus, capture and accelerate ions into the MS.

  • Curtain plate on the TripleTOF 5600

    Curtain plate on the TripleTOF 5600

    This metal plate, in combination with a flow of gas, prevents contaminants from entering the mass spectrometer. It is located between the ESI source and the QJet.