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APPLICATION OVERVIEW : SMALL MOLECULE QUANTIFICATION (MRM)

Quantify your molecule of interest by LC-MS/MS

Are you looking to quantify your molecule, peptide, protein and/or bioconjugate of interest with high precision and reproducibility? If so, the multiple reaction monitoring (MRM) quantification mode will get you the highest level of precision and sensitivity! Using our state-of-the-art TripleTOF 5600 mass spectrometer, we will quantify your molecules of interest with high accuracy, in almost any matrix. This application is ideal for bioanalysis and DMPK (drug metabolism and pharmacokinetics) studies. Although it is not always used for proteomics studies, MRM can also be useful to study proteins with a higher degree of precision. Combined to the right method development protocol, MRM can give very fine details about the expression levels of your protein(s) of interest.

 

For additional sensitivity, we now have access to a top of the line QTRAP 6500+ mass spectrometer. This machine offers a wider dynamic range and can detect the smallest amount of your compound. For more details on the QTRAP 6500+, have a look at our blog post on the matter.

 

If you work with custom molecules, PhenoSwitch Bioscience offers a complete service in small molecule quantification, including the LC-MS/MS method development and sample preparation.

 

Click here to have  a look at our panel of developed LC-MS/MS methods!

Click here to contact our team of experts for your quantification projects!
MRM mass spectrometry service